A Squared Michaelis-Menten Function of Substrate Concentration for Plant Mitochondrial Respiration

A squared michaelis-menten function of substrate concentration for plant mitochondrial respiration.

Dry and Wiskich ([1987] Arch Biochem Biophys 257: 92-99) have published data showing the response of plant mitochondrial respiration to increasing additions of oxaloacetate or malate when these substrates have been depleted by inhibition of succinate dehydrogenase by malonate, and coenzyme A (CoA) has been sequestered as acetyl-CoA by pyruvate dehydrogenase. In the presence of 2-oxoglutarate, i...

Role of substrate unbinding in Michaelis-Menten enzymatic reactions.

The Michaelis-Menten equation provides a hundred-year-old prediction by which any increase in the rate of substrate unbinding will decrease the rate of enzymatic turnover. Surprisingly, this prediction was never tested experimentally nor was it scrutinized using modern theoretical tools. Here we show that unbinding may also speed up enzymatic turnover--turning a spotlight to the fact that its a...

Analytical Expression Pertaining to Concentration of Substrate and Effectiveness Factor for Immobilized Enzymes with Reversible Michaelis Menten Kinetics

Analytical Expression Pertaining to Concentration of Substrate and Effectiveness Factor for Immobilized Enzymes with Reversible Michaelis Menten Kinetics

Analytical Expression Pertaining to Concentration of Substrate and Effectiveness Factor for Immobilized Enzymes with Reversible Michaelis Menten Kinetics